منابع مشابه
Editorial Comments Complement inhibition in renal diseases
The activation of complement and its deleterious consequences have been observed in many renal diseases. Complement contributes to injury in several forms of glomerulonephritis (GN), in acute and chronic humoral rejection after renal transplantation, and at the time of ischaemiaureperfusion injury. It is also thought to accelerate the progression of chronic renal damage. Most of the evidence fo...
متن کاملThe complement system in renal diseases.
The complement system has long been recognized as having a role in immune glomerular disease. This review provides an update on this association, some strategies for the clinical testing of complement in disease, and a brief commentary on current research directions. Evidence of complement activation in glomerulonephritis comes from characteristic patterns of a decrease in the serum concentrati...
متن کاملComplement 5a receptor inhibition improves renal allograft survival.
Complement activation plays a key role in mediating apoptosis, inflammation, and transplant rejection. In this study, the role of the complement 5a receptor (C5aR) was examined in human renal allografts and in an allogenic mouse model of renal transplant rejection. In human kidney transplants with acute rejection, C5aR expression was increased in renal tissue and in cells infiltrating the tubul...
متن کاملThe Relationship between Non-Renal Diseases and Renal Parenchymal Echogenicity in Children with Acute Abdominal Pain
Background Few results have shown that renal parenchymal echogenicity increases in pediatric patients with no concurrent renal diseases. This study aimed to investigate the relation between non-renal diseases and renal cortical echogenicity in children with acute abdominal pain. Materials and Methods This cross- sectional study was conducted among 100 children referred to Amirkola Children’s ...
متن کاملComplement: Deficiency Diseases
Individuals with genetically determined complement deficiencies have a variety of clinical presentations. Most patients present with an increased susceptibility to infection, otherswith a variety of rheumatic diseases, still others with angio-oedema, and in rare instances, patients may even be asymptomatic. The elucidation of the pathophysiological basis for the different clinical presentations...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2003
ISSN: 1460-2385
DOI: 10.1093/ndt/18.2.237